Dr. Shai Efrati is a professor at Sackler School of Medicine and the Sagol School of Neuroscience of Tel Aviv University and the director of the Sagol center for hyperbaric medicine and research at Shamir (Assaf-Harofeh) Medical Center in Israel. The center, under Prof. Efrati management, has become one of the largest hyperbaric center worldwide, currently treating more than 300 patients per day. Prof. Efrati is also the director of Research & Development at the Medical center, affiliated to Tel-Aviv University. Taking the two passions/positions together Dr. Efrati has initiated a research program focusing on the neuroplasticity (regeneration of damage brain tissue) by the use of Hyperbaric Oxygen Therapy (HBOT). In the first clinical studies it was demonstrated that HBOT can induce neuroplasticity in post stroke and Traumatic Brain Injury even years after the acute Insult. The important clinical results gained from the research program have led to fruitful ongoing cooperation including multidiscipline team focusing on the regenerative effects of hyperbaric oxygen in Post-Traumatic Stress Disorder (PTSD), anoxic brain injuries and other types of chronic brain injuries and age related functional decline.