Per- and Polyfluorinated Alkyl Substances (PFAS) are an emerging chemical class of concern to the fire services, mostly because of their use in Aqueous Film-Forming Foams (AFFF). These chemicals have tremendous environmental persistence, they bioaccumulate in humans, and several have demonstrated toxicity. For years these class B foams were deemed safe, and now that they have been released widely into the environment, it has become a serious global problem in drinking water supplies impacted by AFFF. For Firefighters, direct exposure to AFFF has been linked with higher blood sera levels of PFAS, and our research has found another source of PFAS - the water-resistance added to turnout gear is given by the use of PFAS-treated textiles. WIth time, exposure and wear these chemicals will shed from turnout gear and that presents as another source of exposure to PFAS for firefighters. A brief overview of PFAS and the currently known health effects associated with them will be provided, together with an overview of potential exposure routes that firefighters face, and some suggestions where this exposure can be minimized.